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Aldo-keto Reductase Family 1, Member C2 (AKR1C2) Peptide

AKR1C2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN940266

Quick Overview for Aldo-keto Reductase Family 1, Member C2 (AKR1C2) Peptide (ABIN940266)

Target

AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Origin

Mammalian

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    LEAVKLAIEA GFHHIDSAHV YNNEEQVGLA IRSKIADGSV KREDIFYTSK

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of AKR1 C2 antibody,
    Alternative Names: AKR1C2 control peptide, AKR1C2 antibody Blocking Peptide, Anti-AKR1C2 Blocking Peptide, Aldo-Keto Reductase Family 1 Member C2 Blocking Peptide, Dihydrodiol Dehydrogenase 2 Blocking Peptide, Bile Acid Binding protein Blocking Peptide, 3-alpha hydroxysteroid dehydrogenase type III Blocking Peptide, AKR1C-pseudo Blocking Peptide, BABP Blocking Peptide, DD Blocking Peptide, DD2 Blocking Peptide, DDH2 Blocking Peptide, HAKRD Blocking Peptide, HBAB Blocking Peptide, MCDR2 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

    Background

    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

    Molecular Weight

    37 kDa
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