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Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) Peptide

TNFSF12 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN940372
  • Target See all TWEAK (TNFSF12) products
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    LGLLLAVVSL GSRASLSAQE PAQEELVAEE DQDPSELNPQ TEESQDPAPF
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of TNFSF12 antibody,
    Alternative Names: TNFSF12 control peptide, TNFSF12 antibody Blocking Peptide, Anti-TNFSF12 Blocking Peptide, Tumor Necrosis Factor Superfamily 12 Blocking Peptide, APO3L Blocking Peptide, DR3LG Blocking Peptide, MGC129581 Blocking Peptide, MGC20669 Blocking Peptide, TWEAK Blocking Peptide, TNFSF12, TNFSF-12, TNFSF 12, TNFSF-12 Blocking Peptide, TNFSF 12 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    Synonyms
    APO3L Peptide, DR3LG Peptide, TWEAK Peptide, Apo3l Peptide, Dr3l Peptide, Dr3lg Peptide, Tweak Peptide, TNF superfamily member 12 Peptide, tumor necrosis factor (ligand) superfamily, member 12 Peptide, TNFSF12 Peptide, Tnfsf12 Peptide
    Background
    TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.
    Molecular Weight
    17 kDa
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