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Endothelin 3 (EDN3) Peptide

EDN3 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Catalog No. ABIN940397

Quick Overview for Endothelin 3 (EDN3) Peptide (ABIN940397)

Target

Endothelin 3 (EDN3)

Origin

Mammalian

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)

Peptide Type

Synthetic

Sequence

LHFCTQTLDV SSNSRTAEKT DKEEEGKVRG ANRGLCQRRL KSRTNKASRL

Characteristics

A synthetic peptide for use as a blocking control in assays to test for specificity of EDN3 antibody,
Alternative Names: EDN3 control peptide, EDN3 antibody Blocking Peptide, Anti-EDN3 Blocking Peptide, endothelin 3 Blocking Peptide, ET3 Blocking Peptide, MGC15067 Blocking Peptide, MGC61498 Blocking Peptide, EDN3, EDN-3, EDN 3, EDN-3 Blocking Peptide, EDN 3 Blocking Peptide
Endothelin 3 (EDN3) (Middle Region) peptide
EDN3 Reactivity: Human Host: Synthetic BP, WB

Endothelin 3 (EDN3) (C-Term) peptide
EDN3 Reactivity: Human Host: Synthetic BP, WB

Endothelin 3 (EDN3) (C-Term) peptide
EDN3 Reactivity: Human Host: Synthetic BP, WB

Application Notes

Optimal conditions should be determined by the investigator

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

Buffer

PBS

Handling Advice

Avoid repeated freeze/thaw cycles.

Storage

-20 °C

Storage Comment

Store at -20 °C long term.
Target

Endothelin 3 (EDN3)

Background

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

Molecular Weight

24 kDa

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