Actinin, alpha 4 (ACTN4) Peptide
ACTN4
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940431
Quick Overview for Actinin, alpha 4 (ACTN4) Peptide (ABIN940431)
Target
alpha Actinin 4 (ACTN4)
(Actinin, alpha 4 (ACTN4))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- LIHRHRPELI EYDKLRKDDP VTNLNNAFEV AEKYLDIPKM LDAEDIVNTA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of ACTN4 antibody,
Alternative Names: alpha Actinin 4 control peptide, alpha Actinin 4 antibody Blocking Peptide, Anti-alpha Actinin 4 Blocking Peptide, ACTN4 Blocking Peptide, DKFZp686K23158 Blocking Peptide, FSGS Blocking Peptide, FSGS1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
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Background
- Alpha actinins belong to the spectrin superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Alpha actinin is an actin-binding protein with multiple roles in different cell types.
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Molecular Weight
- 100 kDa
Target
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