Estrogen Receptor 1 (ESR1) Peptide
ESR1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940517
Quick Overview for Estrogen Receptor 1 (ESR1) Peptide (ABIN940517)
Target
Estrogen Receptor alpha (ESR1)
(Estrogen Receptor 1 (ESR1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- LLEMLDAHRL HAPTSRGGAS VEETDQSHLA TAGSTSSHSL QKYYITGEAE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of ESR1 antibody,
Alternative Names: ESR1 control peptide, ESR1 antibody Blocking Peptide, Anti-ESR1 Blocking Peptide, estrogen receptor 1 Blocking Peptide, DKFZp686N23123 Blocking Peptide, ER Blocking Peptide, ESR Blocking Peptide, ESRA Blocking Peptide, Era Blocking Peptide, NR3A1 Blocking Peptide, ESR1, ESR-1, ESR 1, ESR-1 Blocking Peptide, ESR 1 Blocking Peptide -
Purification
- Antiserum
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Background
- ESR1 is an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
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Molecular Weight
- 66 kDa
Target
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