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Estrogen Receptor 1 (ESR1) (Middle Region) Peptide

ESR1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5672876
  • Target See all Estrogen Receptor alpha (ESR1) products
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 19
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    RRGGRMLKHK RQRDDGEGRG EVGSAGDMRA ANLWPSPLMI KRSKKNSLAL
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- ESR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Synonyms
    LOC398734 Peptide, AA420328 Peptide, AU041214 Peptide, ER-alpha Peptide, ER[a] Peptide, ERa Peptide, ERalpha Peptide, ESR Peptide, Estr Peptide, Estra Peptide, Nr3a1 Peptide, NR3A1 Peptide, eralpha Peptide, zfER[a] Peptide, ER Peptide, ESRA Peptide, ESTRR Peptide, Era Peptide, akap12 Peptide, cb27 Peptide, esr1 Peptide, fb72g12 Peptide, id:ibd1202 Peptide, sb:cb27 Peptide, si:ch73-192g21.1 Peptide, wu:fb72g12 Peptide, wu:fc21c03 Peptide, Esr Peptide, RNESTROR Peptide, ERALPHA Peptide, er Peptide, esr Peptide, nr3a1 Peptide, XER Peptide, era Peptide, esra Peptide, ERbeta Peptide, xesr-1 Peptide, xlERalpha1 Peptide, xlERalpha2 Peptide, ESR1 Peptide, estrogen receptor 1 L homeolog Peptide, estrogen receptor 1 (alpha) Peptide, estrogen receptor 1 Peptide, A kinase (PRKA) anchor protein 12b Peptide, esr1.L Peptide, Esr1 Peptide, ESR1 Peptide, esr1 Peptide, akap12b Peptide
    Background
    This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

    Alias Symbols: ER, ESR, Era, ESRA, ESTRR, NR3A1

    Protein Size: 312
    Gene ID
    2099
    NCBI Accession
    NM_000125, NP_000116
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