EF-hand calcium binding domain 14 (EFCAB14) (C-Term) Peptide
Quick Overview for EF-hand calcium binding domain 14 (EFCAB14) (C-Term) Peptide (ABIN972662)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- PKEGVKTEND HINLKVAGQD GSVVQFKIKR HTPLSKLMKA YCERQGLSMR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Sumo3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KIAA0494 (EFCAB14) (EF-hand calcium binding domain 14 (EFCAB14))
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Background
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Sumo3 is a ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. It does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. It plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.
Alias Symbols: 2810014B19Rik, AA409334, AW121497, AW536077, D10Ertd345e, SMT3A, SUMO-3, Smt3h1, Smt3B
Protein Size: 110 -
Molecular Weight
- 12 kDa
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Gene ID
- 20610
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NCBI Accession
- NM_019929, NP_064313
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UniProt
- Q9Z172
Target
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