EF-hand calcium binding domain 14 (EFCAB14) (C-Term) Peptide
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- Target See all KIAA0494 (EFCAB14) products
- KIAA0494 (EFCAB14) (EF-hand calcium binding domain 14 (EFCAB14))
- Protein Region
- C-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PKEGVKTEND HINLKVAGQD GSVVQFKIKR HTPLSKLMKA YCERQGLSMR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Sumo3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KIAA0494 (EFCAB14) (EF-hand calcium binding domain 14 (EFCAB14))
- Background
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Sumo3 is a ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. It does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. It plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.
Alias Symbols: 2810014B19Rik, AA409334, AW121497, AW536077, D10Ertd345e, SMT3A, SUMO-3, Smt3h1, Smt3B
Protein Size: 110 - Molecular Weight
- 12 kDa
- Gene ID
- 20610
- NCBI Accession
- NM_019929, NP_064313
- UniProt
- Q9Z172
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