Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (Middle Region) Peptide
ACCN1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN972799
$160.46
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100 μg
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Quick Overview for Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (Middle Region) Peptide (ABIN972799)
Target
ACCN1
(Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACCN1 antibody (Catalog #: ARP35537_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) peptide
ACCN1 Host: Synthetic BP, WB, IHC
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))
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Background
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ACCN1 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.
Alias Symbols: ACCN, ASIC2, ASIC2a, BNC1, BNaC1, MDEG, hBNaC1, ACCN1
Protein Interaction Partner: PICK1,PICK1,ACCN2,ACCN3,PICK1,STOM,ACCN3,Pick1,STOML1
Protein Size: 512 -
Molecular Weight
- 58 kDa
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Gene ID
- 40
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NCBI Accession
- NM_001094, NP_001085
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UniProt
- Q16515
Target
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