Amiloride-Sensitive Cation Channel 3 (ACCN3) Peptide
ACCN3
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN972802
Quick Overview for Amiloride-Sensitive Cation Channel 3 (ACCN3) Peptide (ABIN972802)
Target
ASIC3 (ACCN3)
(Amiloride-Sensitive Cation Channel 3 (ACCN3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACCN3 antibody (Catalog #: ARP35152_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Amiloride-Sensitive Cation Channel 3 (ACCN3) peptide
ACCN3 Host: Synthetic BP, WB, IHC
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
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Background
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ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
Alias Symbols: ACCN3, TNaC1, DRASIC, SLNAC1
Protein Interaction Partner: DLG4,GOPC,LIN7B,MAGI1,ACCN1,ACCN3,CSNK2A1,DLG4,GOPC,INADL,LIN7B,MAGI1,STOM,ACCN1,DLG4,GOPC,LIN7B,MAGI1,PRKACA,STOML1
Protein Size: 531 -
Molecular Weight
- 58 kDa
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Gene ID
- 9311
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NCBI Accession
- NM_004769, NP_004760
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UniProt
- Q9UHC3
Target
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