Alkaline Ceramidase 1 (ACER1) (C-Term) Peptide
ACER1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN972812
Quick Overview for Alkaline Ceramidase 1 (ACER1) (C-Term) Peptide (ABIN972812)
Target
ACER1
(Alkaline Ceramidase 1 (ACER1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequence
- ITFPYGMVTM ALVDANYEMP GETLKVRYWP RDSWPVGLPY VEIRGDDKDC
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACER1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- ACER1 (Alkaline Ceramidase 1 (ACER1))
-
Background
-
ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.
Alias Symbols: ASAH3, MGC138327, MGC138329, ALKCDase1
Protein Size: 264 -
Molecular Weight
- 31 kDa
-
Gene ID
- 125981
-
NCBI Accession
- NM_133492, NP_597999
-
UniProt
- Q8TDN7
Target
-
You are here:
