Actinin, alpha 2 (ACTN2) Peptide
ACTN2
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN972865
Quick Overview for Actinin, alpha 2 (ACTN2) Peptide (ABIN972865)
Target
ACTN2
(Actinin, alpha 2 (ACTN2))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACTN2 antibody (Catalog #: ARP37422_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ACTN2 (Actinin, alpha 2 (ACTN2))
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Background
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The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function.
Alias Symbols: 1110008F24Rik
Protein Interaction Partner: Myoz1,Myoz2,Myoz3,Myoz1,Myoz2,Raver1
Protein Size: 894 -
Molecular Weight
- 98 kDa
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Gene ID
- 11472
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NCBI Accession
- NM_033268, NP_150371
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UniProt
- Q9JI91
Target
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