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ADAM Metallopeptidase Domain 19 (Adam19) Peptide

Adam19 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN972897

Quick Overview for ADAM Metallopeptidase Domain 19 (Adam19) Peptide (ABIN972897)

Target

ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Origin

Human

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-ADAM19 antibody (Catalog #: ARP49780_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

    Background

    ADAM19 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants.

    Alias Symbols: FKSG34, MADDAM, MLTNB

    Protein Interaction Partner: A2M,COPB1,FURIN,NRG1,TNFSF11,ABI2,ABI2,COPB1,COPB1,ESF1,SH3GL2,UBC

    Protein Size: 956

    Molecular Weight

    82 kDa

    Gene ID

    8728

    NCBI Accession

    NM_023038, NP_075525

    UniProt

    Q9H013
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