Adenosine A2b Receptor (ADORA2B) (C-Term) Peptide
Quick Overview for Adenosine A2b Receptor (ADORA2B) (C-Term) Peptide (ABIN972952)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- THGNSAMNPI VYAFRIQKFR VTFLKIWNDH FRCQPAPPID EDLPEERPDD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADORA2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Adenosine A2b Receptor (ADORA2B)
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Background
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The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.
Alias Symbols: ADORA2
Protein Interaction Partner: ADA,DRD1,EPB41L2,GNAI2,GNAO1,GNAS,GNAZ,GRM1,P2RY1,ADA,DRD1,GNAI2,GRM1,P2RY1
Protein Size: 326 -
Molecular Weight
- 36 kDa
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Gene ID
- 136
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NCBI Accession
- NM_000676, NP_000667
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UniProt
- P29275
Target
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