Adrenergic, beta-2-, Receptor, Surface (ADRB2) (Middle Region) Peptide
ADRB2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN972964
Quick Overview for Adrenergic, beta-2-, Receptor, Surface (ADRB2) (Middle Region) Peptide (ABIN972964)
Target
beta 2 Adrenergic Receptor (ADRB2)
(Adrenergic, beta-2-, Receptor, Surface (ADRB2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADRB2 antibody (Catalog #: AVARP00006_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Adrenergic, beta-2-, Receptor, Surface (ADRB2) peptide (Ovalbumin)
ADRB2 Reactivity: Mouse Host: Synthetic WB, Imm, SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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Background
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This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Protein Interaction Partner: EIF2B1,SLC9A3R1,SLC9A3R2,ADRB3,AKAP12,AKAP5,ARR3,ARRB1,CSK,EIF2B1,GNA11,GNA14,GNA15,GPRASP1,GRB2,GRK5,GRK6,HTR4,IL1B,INSR,KCNJ6,KCNJ9,NOS1,OPRD1,PRKCD,SLC9A3R1,SLC9A3R2,SRC,ADRB2,ADRBK1,AKAP12,Arrb2,EIF2B1,GRB2,GRK6,KCNJ3,KCNJ5,OPRD1,PPP3CA,SLC9A3R1,SLC9A3R2,SRC,UBC
Protein Size: 413 -
Molecular Weight
- 46 kDa
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Gene ID
- 154
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NCBI Accession
- NM_000024, NP_000015
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UniProt
- P07550
Target
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