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Adrenergic, beta-2-, Receptor, Surface (ADRB2) (Middle Region) Peptide

ADRB2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5672831
  • Target See all beta 2 Adrenergic Receptor (ADRB2) products
    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 10
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    RQLQKIDKSE GRFHVQNLSQ VEQDGRTGHG LRRSSKFCLK EHKALKTLGI
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- ADRB2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
    Synonyms
    zgc:162188 Peptide, adrb2 Peptide, Adrb-2 Peptide, Badm Peptide, Gpcr7 Peptide, ADRB2R Peptide, ADRBR Peptide, B2AR Peptide, BAR Peptide, BETA2AR Peptide, adrenoceptor beta 2 Peptide, adrenoceptor beta 2, surface b Peptide, beta2-adrenergic receptor Peptide, adrenergic receptor, beta 2 Peptide, ADRB2 Peptide, adrb2b Peptide, LOC100136153 Peptide, Adrb2 Peptide
    Background
    This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

    Alias Symbols: BAR, B2AR, ADRBR, ADRB2R, BETA2AR

    Protein Size: 413
    Gene ID
    154
    NCBI Accession
    NM_000024, NP_000015
    UniProt
    P07550
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