Amino-terminal Enhancer of Split (AES) Peptide
AES
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN972975
Quick Overview for Amino-terminal Enhancer of Split (AES) Peptide (ABIN972975)
Target
AES
(Amino-terminal Enhancer of Split (AES))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AES antibody (Catalog #: ARP36553_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AES (Amino-terminal Enhancer of Split (AES))
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Background
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AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genesThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AES-1, AES-2, ESP1, GRG, GRG5, TLE5
Protein Interaction Partner: AES,RELA,SIX1,SIX2,SIX3,SIX6,PTRH2,AR,ATN1,CCL7,GABARAP,GFI1B,GTF2E1,HMGB1,MED31,MSX1,POU2F1,PRDM1,PTRH2,RELA,RPL18A,SH3GL3,SIX1,SIX2,SIX3,SIX6,SNCAIP,AES,AR,GTF2E1,HMGB1,HNF1A,HNRNPAB,MED31,PTRH2,RELA,RUNX1,SH3GL3,SIX3,SIX6,STYXL1,TLE1,TLE3
Protein Size: 197 -
Molecular Weight
- 22 kDa
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Gene ID
- 166
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NCBI Accession
- NM_001130, NP_001121
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UniProt
- Q08117
Target
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