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A Kinase (PRKA) Anchor Protein 7 (AKAP7) (Middle Region) Peptide

AKAP7 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973060

Quick Overview for A Kinase (PRKA) Anchor Protein 7 (AKAP7) (Middle Region) Peptide (ABIN973060)

Target

AKAP7 (A Kinase (PRKA) Anchor Protein 7 (AKAP7))

Origin

Human

Source

  • 9
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-AKAP7 antibody (Catalog #: ARP36795_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    AKAP7 (A Kinase (PRKA) Anchor Protein 7 (AKAP7))

    Background

    AKAP7 is a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined. This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.

    Alias Symbols: AKAP18, AKAP15

    Protein Interaction Partner: PRKAR1A,PRKAR2A,MEPCE,PRKAR2A,USP4

    Protein Size: 326

    Molecular Weight

    37 kDa

    Gene ID

    9465

    NCBI Accession

    NM_016377, NP_057461

    UniProt

    Q9P0M2
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