Dihydrodiol Dehydrogenase (DDH) (N-Term) Peptide
DDH
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973074
Quick Overview for Dihydrodiol Dehydrogenase (DDH) (N-Term) Peptide (ABIN973074)
Target
AKR1C1 (DDH)
(Dihydrodiol Dehydrogenase (DDH))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- DSAHLYNNEE QVGLAIRSKI ADGSVKREDI FYTSKLWCNS HRPELVRPAL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKR1C1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
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Background
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DDH, DDH1, H-37, HAKRC, MBAB, MGC8954, HBAB, DD1/DD2
Protein Size: 323 -
Molecular Weight
- 36 kDa
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Gene ID
- 1645
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NCBI Accession
- NM_001353, NP_001344
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UniProt
- Q04828
Target
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