Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (N-Term) Peptide
AKR1C2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973076
Quick Overview for Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (N-Term) Peptide (ABIN973076)
Target
AKR1C2
(Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequence
- DGSVKREDIF YTSKLWSNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKR1C2 Antibody(ARP53507_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
-
Background
-
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8
Protein Interaction Partner: AKR1C2
Protein Size: 323 -
Molecular Weight
- 37 kDa
-
Gene ID
- 1646
-
NCBI Accession
- NM_205845, NP_995317
-
UniProt
- P52895
Target
-
You are here:
