Aldo-Keto Reductase Family 1, Member D1 (AKR1D1) (Middle Region) Peptide
AKR1D1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973078
Quick Overview for Aldo-Keto Reductase Family 1, Member D1 (AKR1D1) (Middle Region) Peptide (ABIN973078)
Target
AKR1D1
(Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- YVDLYIIEVP MAFKPGDEIY PRDENGKWLY HKSNLCATWE AMEACKDAGL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKR1D1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))
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Background
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The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
Alias Symbols: 3o5bred, CBAS2, SRD5B1
Protein Size: 326 -
Molecular Weight
- 37 kDa
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Gene ID
- 6718
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NCBI Accession
- NM_005989, NP_005980
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UniProt
- P51857
Target
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