Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) (N-Term) Peptide
AKR7A2
Reactivity: Human
Host: Synthetic
WB, BP
Catalog No. ABIN973080
$160.46
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100 μg
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Quick Overview for Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) (N-Term) Peptide (ABIN973080)
Target
AKR7A2
(Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP)
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Protein Region
- N-Term
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Sequence
- SETILGGLGL GLGGGDCRVK IATKANPWDG KSLKPDSVRS QLETSLKRLQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKR7A2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
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Background
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The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.
Alias Symbols: AFAR, AFAR1, AFB1-AR1, AKR7
Protein Interaction Partner: AKR7A3,F2,AKR7A3,TRIM63,UBC
Protein Size: 359 -
Molecular Weight
- 39 kDa
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Gene ID
- 8574
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NCBI Accession
- NM_003689, NP_003680
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UniProt
- O43488
Target
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