V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) Peptide
AKT2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973084
$160.46
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100 μg
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Quick Overview for V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) Peptide (ABIN973084)
Target
AKT2
(V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKT2 antibody (Catalog #: ARP30321_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) peptide
AKT2 Host: Synthetic WB, CP Sodium azide
V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) peptideAKT2 Host: Synthetic WB, CP Sodium azide
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
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Background
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AKT2 belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene encoding AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PKBBETA, PRKBB, RAC-BETA, PKBB, HIHGHH
Protein Interaction Partner: APPL1,CHUK,TCL1A,AKT1,AKT1S1,AKT2,APPL1,CHUK,ESR1,FOXO4,FSHR,GSK3B,HSP90AA1,MTCP1,PDPK1,RAB3D,SH3RF1,SLC2A4,TCL1A,TCL1B,TRIB3,TSC2,XIAP,APPL1,CHUK,GSK3B,MTCP1,PRKDC,SH3RF1,TCL1A,TCL1B
Protein Size: 481 -
Molecular Weight
- 56 kDa
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Gene ID
- 208
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NCBI Accession
- NM_001626, NP_001617
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UniProt
- P31751
Target
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