Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1) (C-Term) Peptide
ALDH3A1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Quick Overview for Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1) (C-Term) Peptide (ABIN973104)
Target
ALDH3A1
(Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- C-Term
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Sequence
- KFMNSGQTCV APDYILCDPS IQNQIVEKLK KSLKEFYGED AKKSRDYGRI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALDH3A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))
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Background
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Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: ALDH3, ALDHIII, MGC10406
Protein Interaction Partner: ALDH3A1
Protein Size: 453 -
Molecular Weight
- 50 kDa
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Gene ID
- 218
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NCBI Accession
- NM_000691, NP_000682
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UniProt
- P30838
Target
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