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Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1) (Middle Region) Peptide

ALDH5A1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973114

Quick Overview for Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1) (Middle Region) Peptide (ABIN973114)

Target

ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    AFFLEWFSEE ARRVYGDIIH TPAKDRRALV LKQPIGVAAV ITPWNFPSAM

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-ALDH5A1 Antibody(ARP59587_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

    Background

    This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

    Alias Symbols: SSADH, SSDH

    Protein Interaction Partner: ABAT,ABAT

    Protein Size: 535

    Molecular Weight

    57 kDa

    Gene ID

    7915

    NCBI Accession

    NM_001080, NP_001071

    UniProt

    P51649
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