Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1) (Middle Region) Peptide
Quick Overview for Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1) (Middle Region) Peptide (ABIN973114)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- AFFLEWFSEE ARRVYGDIIH TPAKDRRALV LKQPIGVAAV ITPWNFPSAM
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALDH5A1 Antibody(ARP59587_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))
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Background
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This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: SSADH, SSDH
Protein Interaction Partner: ABAT,ABAT
Protein Size: 535 -
Molecular Weight
- 57 kDa
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Gene ID
- 7915
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NCBI Accession
- NM_001080, NP_001071
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UniProt
- P51649
Target
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