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Aldolase A, Fructose-Bisphosphate (ALDOA) Peptide

ALDOA Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973119

Quick Overview for Aldolase A, Fructose-Bisphosphate (ALDOA) Peptide (ABIN973119)

Target

ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Origin

Human

Source

  • 8
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-ALDOA antibody (Catalog #: ARP48130_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

    Background

    ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.

    Alias Symbols: ALDA, MGC10942, MGC17716, MGC17767, GSD12

    Protein Interaction Partner: ALDOA,ATP6V1E1,DYNLL1,GPD2,MYOC,PLD2,SUMO4,TGM2,TUBB,XRN1,ATP6V1E1,FANCA,OSBPL10,PLD2,USP15,XRN1

    Protein Size: 364

    Molecular Weight

    39 kDa

    Gene ID

    226

    NCBI Accession

    NM_000034, NP_000025

    UniProt

    P04075
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