AlkB, Alkylation Repair Homolog 3 (ALKBH3) (Middle Region) Peptide
ALKBH3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973135
Quick Overview for AlkB, Alkylation Repair Homolog 3 (ALKBH3) (Middle Region) Peptide (ABIN973135)
Target
ALKBH3
(AlkB, Alkylation Repair Homolog 3 (ALKBH3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALKBH3 antibody (Catalog #: ARP55429_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
-
Background
-
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine.The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1519 AB042029.1 2-1520
Alias Symbols: ABH3, DEPC-1, DEPC1, MGC118790, MGC118792, MGC118793, PCA1
Protein Size: 286 -
Molecular Weight
- 33 kDa
-
Gene ID
- 221120
-
NCBI Accession
- NM_139178, NP_631917
-
UniProt
- Q96Q83
Target
-
You are here:
