Autocrine Motility Factor Receptor (AMFR) Peptide
AMFR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973172
Quick Overview for Autocrine Motility Factor Receptor (AMFR) Peptide (ABIN973172)
Target
AMFR
(Autocrine Motility Factor Receptor (AMFR))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AMFR antibody (Catalog #: ARP42995_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AMFR (Autocrine Motility Factor Receptor (AMFR))
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Background
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Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000).[supplied by OMIM].
Alias Symbols: GP78, RNF45
Protein Interaction Partner: GPI,UBE2D2,UBE2G2,VCP,CD3D,CFTR,CYP3A4,DERL1,DERL2,DERL3,FAF2,HSPD1,RNF5,RPL5,SELS,SVIP,UBE2D2,UBE2G2,UFD1L,Ube2g2,VCP
Protein Size: 482 -
Molecular Weight
- 53 kDa
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Gene ID
- 267
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NCBI Accession
- NM_013446
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UniProt
- Q9UKV5
Target
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