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Autocrine Motility Factor Receptor (AMFR) Peptide

AMFR Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973172
  • Target See all AMFR products
    AMFR (Autocrine Motility Factor Receptor (AMFR))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-AMFR antibody (Catalog #: ARP42995_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    AMFR (Autocrine Motility Factor Receptor (AMFR))
    Background
    Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000).[supplied by OMIM].

    Alias Symbols: GP78, RNF45

    Protein Interaction Partner: GPI,UBE2D2,UBE2G2,VCP,CD3D,CFTR,CYP3A4,DERL1,DERL2,DERL3,FAF2,HSPD1,RNF5,RPL5,SELS,SVIP,UBE2D2,UBE2G2,UFD1L,Ube2g2,VCP

    Protein Size: 482
    Molecular Weight
    53 kDa
    Gene ID
    267
    NCBI Accession
    NM_013446
    UniProt
    Q9UKV5
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