Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) Peptide
ANP32A
Reactivity: Human
Host: Synthetic
WB, BP, IHC
Catalog No. ABIN973240
Quick Overview for Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) Peptide (ABIN973240)
Target
PHAP1 (ANP32A)
(Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ANP32A antibody (Catalog #: ARP40203_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))
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Background
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ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.
Alias Symbols: LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1
Protein Interaction Partner: ESR1,RARA,THRB,ADAP1,APEX1,ATXN1,AXIN1,E4F1,ELAVL1,HSPB3,KPNA1,KPNA5,KPNA6,MAP1B,NSFL1C,PTPRC,SET,ADAP1,APEX1,ATXN1,AXIN1,HIST3H3,HIST4H4,HSPB3,MAP1B,MEPCE,SET,TAF1A
Protein Size: 249 -
Molecular Weight
- 29 kDa
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Gene ID
- 8125
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NCBI Accession
- NM_006305, NP_006296
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UniProt
- P39687
Target
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