Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) Peptide
AP1G1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973273
Quick Overview for Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) Peptide (ABIN973273)
Target
gamma 1 Adaptin (AP1G1)
(Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AP1G1 antibody (Catalog #: ARP51923_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- gamma 1 Adaptin (AP1G1) (Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))
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Background
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Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. AP1G1 is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family.Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADTG, CLAPG1, MGC18255
Protein Interaction Partner: AP1AR,AP1S1,AFTPH,AP1AR,AP1B1,AP1G1,AP1M2,AP1S1,AP1S2,ARF1,CLINT1,CLTC,DNER,MAP1A,RABEP1,RABGEF1,SPTB,SYNRG,SYP,AP1B1,AP1M1,AP1M2,AP1S1,AP1S2,AP2M1,AP2S1,ARF1,CLINT1,KIF13A,NECAP1,NECAP2,RAB5A,RABEP1,SYNRG,SYP
Protein Size: 822 -
Molecular Weight
- 91 kDa
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Gene ID
- 164
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NCBI Accession
- NM_001128, NP_001119
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UniProt
- O43747
Target
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