APC Regulator of WNT Signaling Pathway 2 (APC2) Peptide
APC2
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all APC2 products
- APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-APC2 antibody (Catalog #: ARP50526_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
- Background
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APC2 belongs to the adenomatous polyposis coli (APC) family. It contains 6 ARM repeats. APC2 promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. It may function in Wnt signaling.
Alias Symbols: APCL
Protein Interaction Partner: CTNNB1,MAPRE1,MAPRE3,ACTA1,ANAPC1,ANAPC10,ANAPC11,ANAPC4,ANAPC5,ANAPC7,AXIN2,Axin1,CDC16,CDC23,CDC26,CDC27,CDH1,CTNNB1
Protein Size: 2303 - Molecular Weight
- 244 kDa
- Gene ID
- 10297
- NCBI Accession
- NM_005883, NP_005874
- UniProt
- Q9UJX6
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