APC Regulator of WNT Signaling Pathway 2 (APC2) Peptide
APC2
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN973293
Quick Overview for APC Regulator of WNT Signaling Pathway 2 (APC2) Peptide (ABIN973293)
Target
APC2
(APC Regulator of WNT Signaling Pathway 2 (APC2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-APC2 antibody (Catalog #: ARP50526_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
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Background
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APC2 belongs to the adenomatous polyposis coli (APC) family. It contains 6 ARM repeats. APC2 promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. It may function in Wnt signaling.
Alias Symbols: APCL
Protein Interaction Partner: CTNNB1,MAPRE1,MAPRE3,ACTA1,ANAPC1,ANAPC10,ANAPC11,ANAPC4,ANAPC5,ANAPC7,AXIN2,Axin1,CDC16,CDC23,CDC26,CDC27,CDH1,CTNNB1
Protein Size: 2303 -
Molecular Weight
- 244 kDa
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Gene ID
- 10297
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NCBI Accession
- NM_005883, NP_005874
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UniProt
- Q9UJX6
Target
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