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APC Regulator of WNT Signaling Pathway 2 (APC2) Peptide

APC2 Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN973293
  • Target See all APC2 products
    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-APC2 antibody (Catalog #: ARP50526_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
    Background
    APC2 belongs to the adenomatous polyposis coli (APC) family. It contains 6 ARM repeats. APC2 promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. It may function in Wnt signaling.

    Alias Symbols: APCL

    Protein Interaction Partner: CTNNB1,MAPRE1,MAPRE3,ACTA1,ANAPC1,ANAPC10,ANAPC11,ANAPC4,ANAPC5,ANAPC7,AXIN2,Axin1,CDC16,CDC23,CDC26,CDC27,CDH1,CTNNB1

    Protein Size: 2303
    Molecular Weight
    244 kDa
    Gene ID
    10297
    NCBI Accession
    NM_005883, NP_005874
    UniProt
    Q9UJX6
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