N-Acylaminoacyl-Peptide Hydrolase (APEH) (Middle Region) Peptide
APEH
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all APEH products
- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GSTGFGQDSI LSLPGNVGHQ DVKDVQFAVE QVLQEEHFDA SHVALMGGSH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-APEH Antibody(ARP48182_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
- Synonyms
- AARE Peptide, ACPH Peptide, APH Peptide, D3F15S2 Peptide, D3S48E Peptide, DNF15S2 Peptide, OPH Peptide, AAP Peptide, cb5 Peptide, sb:cb5 Peptide, wu:fi37d02 Peptide, acylaminoacyl-peptide hydrolase Peptide, acylpeptide hydrolase Peptide, APEH Peptide, Apeh Peptide, apeh Peptide
- Background
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APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
Alias Symbols: ACPH, APH, D3F15S2, D3S48E, DNF15S2, MGC2178, OPH, AARE
Protein Interaction Partner: APEH,KIAA0174,SHBG,TMEM62,UBA5,APEH,KIAA0174,UBA5
Protein Size: 732 - Molecular Weight
- 81 kDa
- Gene ID
- 327
- NCBI Accession
- NM_001640, NP_001631
- UniProt
- P13798
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