Aquarius Homolog (AQR) (C-Term) Peptide
Quick Overview for Aquarius Homolog (AQR) (C-Term) Peptide (ABIN973355)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- DTTPSETGAT STPEAIPALS ETTPTVVGAV SAPAEANTPQ DATSAPEETK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AQR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AQR (Aquarius Homolog (AQR))
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Background
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AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Alias Symbols: DKFZp686B23123, IBP160, KIAA0560, fSAP164
Protein Size: 1485 -
Molecular Weight
- 171 kDa
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Gene ID
- 9716
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NCBI Accession
- NM_014691, NP_055506
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UniProt
- O60306
Target
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