ADP-Ribosylation Factor 6 (ARF6) Peptide
ARF6
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all ARF6 products
- ARF6 (ADP-Ribosylation Factor 6 (ARF6))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ARF6 antibody (Catalog #: ARP54598_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ARF6 (ADP-Ribosylation Factor 6 (ARF6))
- Background
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ARF6 is a member of the human ARF family, which is part of the RAS superfamily. They are small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF6 is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp564M0264
Protein Interaction Partner: AP1B1,AP3B1,AP3D1,ARFIP2,ARRB1,ARRB2,ASAP2,ASAP3,ATP6V0C,CAPN1,CHRM3,CYTH2,EXOC5,EZR,MPP5,PIP5K1A,PIP5K1C,PLD1,RAB11FIP3,ZNF709,AP3B1,AP3S2,ARFIP2,ARRB1,ARRB2,CHRM3,CYTH2,DHPS,DYNC1H1,EIF6,EPPK1,EXOC5,GART,IQGAP1,KIAA0368,LRPPRC,MEPCE,PABPC4,PIP5K1C,PLD1,RALA,RUVBL2,YARS
Protein Size: 175 - Molecular Weight
- 20 kDa
- Gene ID
- 382
- NCBI Accession
- NM_001663, NP_001654
- UniProt
- P62330
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