ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3) (N-Term) Peptide
ARFGAP3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973373
Quick Overview for ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3) (N-Term) Peptide (ABIN973373)
Target
ARFGAP3
(ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- FHQHGCSTND TNAKYNSRAA QLYREKIKSL ASQATRKHGT DLWLDSCVVP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ARFGAP3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3) peptide
ARFGAP3 Reactivity: Human, Mouse, Cow, Dog, Rat Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
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Background
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The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
Alias Symbols: ARFGAP1, FLJ45618
Protein Interaction Partner: SMAD2
Protein Size: 516 -
Molecular Weight
- 57 kDa
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Gene ID
- 26286
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NCBI Accession
- NM_014570, NP_055385
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UniProt
- Q9NP61
Target
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