Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (C-Term) Peptide
ARNT
Reactivity: Rat
Host: Synthetic
BP, WB
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- Target See all ARNT products
- ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
- Protein Region
- C-Term
- Origin
- Rat
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SNEQHVQPTS AQPSSQPEVF QEMLSMLGDQ SNTYNNEEFP DLTMFPPFSE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Arnt Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
- Background
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Arnt is required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
Alias Symbols: Arnt1, Arnt
Protein Size: 800 - Molecular Weight
- 88 kDa
- Gene ID
- 25242
- NCBI Accession
- NM_012780, NP_036912
- UniProt
- P41739
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