Arylsulfatase A (ARSA) (N-Term) Peptide
Quick Overview for Arylsulfatase A (ARSA) (N-Term) Peptide (ABIN973462)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ARSA antibody (Catalog #: ARP54528_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Arylsulfatase A (ARSA)
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Background
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ARSA hydrolyzes cerebroside sulfate. Defects in ARSA are a cause of leukodystrophy metachromatic (MLD).The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Multiple alternatively spliced transcript variants, one of which encodes a distinct protein, have been described for this gene.
Alias Symbols: MLD
Protein Interaction Partner: ARSA,BMPR2,CTSL1,GAL3ST1,ARSA
Protein Size: 507 -
Molecular Weight
- 56 kDa
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Gene ID
- 410
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NCBI Accession
- NM_000487, NP_000478
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UniProt
- P15289
Target
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