Activating Transcription Factor 2 (ATF2) Peptide
ATF2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN973546
Quick Overview for Activating Transcription Factor 2 (ATF2) Peptide (ABIN973546)
Target
ATF2
(Activating Transcription Factor 2 (ATF2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ATF2 antibody (Catalog #: ARP34151_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Activating Transcription Factor 2 (ATF2) peptide
ATF2 Reactivity: Human, Rat, Cow, Dog Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATF2 (Activating Transcription Factor 2 (ATF2))
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Background
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ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
Alias Symbols: HB16, CREB2, TREB7, CRE-BP1
Protein Interaction Partner: ATM,MAPK11,MAPK14,MAPK14,MAPK14,MAPK3,MAPK9,NBN,RB1,YY1,AR,ATF2,ATF7,CEBPA,CEBPB,CEBPG,CREB5,CSNK2A1,CSNK2A2,EDF1,FOS,GTF2F2,HIST2H2BE,HMGA1,JDP2,JUN,MAPK11,MAPK13,MAPK14,MAPK8,MAPK9,MAPKAPK5,NBN,NCOA6,RB1,RPS6KA5,RUVBL2,SMAD3,SMAD4,UBE2I,UTF1,XPO1,ATF2,CEBPA,CREBBP,CSNK2A1,CSNK2A2,FOS,HDAC4,HMGA1,IRF2BP1,JDP2,JUN,MAPK1,MAPK13,MAPK14,MAPK8,NCOA6,PML,RB1,RUVBL2,SMAD3,SMAD4,UBE2I,UTF1
Protein Size: 505 -
Molecular Weight
- 55 kDa
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Gene ID
- 1386
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NCBI Accession
- NM_001880, NP_001871
Target
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