Activating Transcription Factor 5 (ATF5) (Middle Region) Peptide
ATF5
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973556
Quick Overview for Activating Transcription Factor 5 (ATF5) (Middle Region) Peptide (ABIN973556)
Target
ATF5
(Activating Transcription Factor 5 (ATF5))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ATF5 antibody (Catalog #: ARP57977_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATF5 (Activating Transcription Factor 5 (ATF5))
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Background
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ATF5 belongs to the bZIP family. It is transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Loss of ATF5 is associated with hepatocellular carcinoma.
Alias Symbols: ATFX, FLJ34666, HMFN0395
Protein Interaction Partner: DISC1,CCND3,CDC34,CEBPG,DISC1,GABBR1,GABBR2,CD34,CDC34,DISC1,GABBR1,TRIB3,UBC
Protein Size: 282 -
Molecular Weight
- 31 kDa
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Gene ID
- 22809
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NCBI Accession
- NM_012068, NP_036200
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UniProt
- B3KND3
Target
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