ATG16 Autophagy Related 16-Like 1 (ATG16L1) (Middle Region) Peptide
ATG16L1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973569
Quick Overview for ATG16 Autophagy Related 16-Like 1 (ATG16L1) (Middle Region) Peptide (ABIN973569)
Target
ATG16L1
(ATG16 Autophagy Related 16-Like 1 (ATG16L1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ATG16L1 antibody (Catalog #: ARP54269_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))
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Background
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Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy. Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]).[supplied by OMIM].
Alias Symbols: APG16L, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30, ATG16A
Protein Interaction Partner: ATG16L1,ATG5,ATG12,IKBKG
Protein Size: 588 -
Molecular Weight
- 66 kDa
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Gene ID
- 55054
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NCBI Accession
- NM_017974, NP_060444
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UniProt
- Q676U5
Target
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