ATG5 Autophagy Related 5 (ATG5) Peptide
ATG5
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN973582
Quick Overview for ATG5 Autophagy Related 5 (ATG5) Peptide (ABIN973582)
Target
ATG5
(ATG5 Autophagy Related 5 (ATG5))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ATG5 antibody (Catalog #: ARP54267_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATG5 (ATG5 Autophagy Related 5 (ATG5))
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Background
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ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Alias Symbols: APG5, APG5L, ASP, hAPG5, APG5-LIKE
Protein Interaction Partner: ATG10,ATG12,ATG16L1,ATG5,ATG12,IMPDH2
Protein Size: 275 -
Molecular Weight
- 32 kDa
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Gene ID
- 9474
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NCBI Accession
- NM_004849, NP_004840
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UniProt
- Q9H1Y0
Target
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