Aurora Kinase A (AURKA) Peptide
AURKA
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Quick Overview for Aurora Kinase A (AURKA) Peptide (ABIN973656)
Target
Aurora A (AURKA)
(Aurora Kinase A (AURKA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AURKA antibody (Catalog #: ARP30876_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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Background
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AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Alias Symbols: AIK, ARK1, AURA, AURORA2, BTAK, MGC34538, STK15, STK6, STK7, PPP1R47
Protein Interaction Partner: CHFR,RASA1,TP53,AURKA,AURKAIP1,BRCA1,C13orf34,CDC20,CDC25B,CHFR,CKAP5,GSK3B,MBD3,NDC80,NIN,NME1,NUF2,PML,PPP1CA,PPP1CC,PRKACA,TACC1,TACC3,TP53,TPX2,UBE2N,BRCA1,CDC20,CDKN2A,CHFR,KIF2C,MBD3,NFKBIA,NIN,NME1,PML,RAB10,SOD2,TACC1,TP53,TPX2,UBE2L3,UBE2N
Protein Size: 403 -
Molecular Weight
- 46 kDa
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Gene ID
- 6790
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NCBI Accession
- NM_003600, NP_003591
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UniProt
- O14965
Target
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