Aurora Kinase C (AURKC) (Middle Region) Peptide
AURKC
Reactivity: Human
Host: Synthetic
BP, WB
Quick Overview for Aurora Kinase C (AURKC) (Middle Region) Peptide (ABIN973657)
Target
Aurora Kinase C (AURKC)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AURKC antibody (Catalog #: ARP53575_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Aurora Kinase C (AURKC)
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Background
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AURKC may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
Alias Symbols: AIE2, AIK3, AurC, STK13, aurora-C, ARK3, SPGF5
Protein Interaction Partner: INCENP,TACC2
Protein Size: 309 -
Molecular Weight
- 34 kDa
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Gene ID
- 6795
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NCBI Accession
- NM_001015878, NP_001015878
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UniProt
- Q9UQB9
Target
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