BCL2-Associated Athanogene (BAG1) (N-Term) Peptide
BAG1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973711
Quick Overview for BCL2-Associated Athanogene (BAG1) (N-Term) Peptide (ABIN973711)
Target
BAG1
(BCL2-Associated Athanogene (BAG1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LIFKGKSLKE METPLSALGI QDGCRVMLIG KKNSPQEEVE LKKLKHLEKS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-BAG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BAG1 (BCL2-Associated Athanogene (BAG1))
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Background
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The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Alias Symbols: HAP, RAP46
Protein Interaction Partner: HSPA4,AR,BCL2,BCL2L1,ESR1,HBEGF,HSPA1A,HSPA1B,HSPA8,MET,NR3C1,PDGFRB,PPP1R15A,PSMD1,RAF1,RARA,RB1,SIAH1,STUB1,VDR,AR,BCL2,ESR1,HBEGF,HSPA1A,HSPA4,HSPA8,MAPT,NR3C1,PPP1R15A,RAF1,RARA,RB1,SIAH1,STUB1,TP53,UBC,VDR
Protein Size: 230 -
Molecular Weight
- 25 kDa
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Gene ID
- 573
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NCBI Accession
- NM_001172415, NP_001165886
Target
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