BCL2-Associated X Protein (BAX) Peptide
BAX
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN973743
Quick Overview for BCL2-Associated X Protein (BAX) Peptide (ABIN973743)
Target
BAX
(BCL2-Associated X Protein (BAX))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-BAX antibody (Catalog #: AVARP02020_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BAX (BCL2-Associated X Protein (BAX))
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Background
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BAX encodes a protein that belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. BAX expression is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
Alias Symbols: BCL2L4
Protein Interaction Partner: TP53,TP53,TP73,BBC3,BCL2,BCL2,BCL2L1,BCL2L1,BID,MOAP1,NOL3,BAK1,BBC3,BCL2,BCL2A1,BCL2L1,BCL2L10,BID,ERN1,KCNA3,MCL1,MOAP1,NOL3,PMAIP1,PPP1CA,SFN,SH3GLB1,SLC25A4,VDAC1,YWHAQ,GTF2B,MUC1,TAF1,TBP,TP53,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L10,BCL2L2,BNIPL,Bak1,CRYAA,CRYAB,HSPD1,MCL1,MEPCE,MOAP1,MOAP1,OYE2,PMAIP1,SH3GLB1,SH3GLB1,SLC25A4,SNCA,TOMM22,TOMM40,UBC,VDAC1,YWHAQ
Protein Size: 192 -
Molecular Weight
- 21 kDa
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Gene ID
- 581
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NCBI Accession
- NM_138761, NP_620116
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UniProt
- Q07812
Target
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