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Bardet-Biedl Syndrome 2 (BBS2) (N-Term) Peptide

BBS2 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN973751

Quick Overview for Bardet-Biedl Syndrome 2 (BBS2) (N-Term) Peptide (ABIN973751)

Target

BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

N-Term

Sequence

GSDLFWTVTG DNVNSLALCD FDGDGKKELL VGSEDFDIRV FKEDEIVAEM

Characteristics

This is a synthetic peptide designed for use in combination with anti-BBS2 Antibody(ARP59752_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Bardet-Biedl Syndrome 2 (BBS2) peptide
BBS2 Host: Synthetic BP, WB, IHC

Bardet-Biedl Syndrome 2 (BBS2) peptide
BBS2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Bardet-Biedl Syndrome 2 (BBS2) (Middle Region) peptide
BBS2 Reactivity: Human Host: Synthetic BP, WB

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Background

This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.

Alias Symbols: BBS, MGC20703

Protein Interaction Partner: PSME3,PSME3

Protein Size: 721

Molecular Weight

80 kDa

Gene ID

583

NCBI Accession

NM_031885, NP_114091

UniProt

Q9BXC9

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