B-Cell CLL/lymphoma 7A (BCL7A) (Middle Region) Peptide
BCL7A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973789
Quick Overview for B-Cell CLL/lymphoma 7A (BCL7A) (Middle Region) Peptide (ABIN973789)
Target
BCL7A
(B-Cell CLL/lymphoma 7A (BCL7A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- QENSSNSSPA PEPNSAVPSD GTEAKVDEAQ ADGKEHPGAE DASDEQNSQS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-BCL7A Antibody(ARP57508_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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B-Cell CLL/lymphoma 7A (BCL7A) peptide
BCL7A Reactivity: Human, Cow, Dog, Mouse, Pig, Rat Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))
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Background
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This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: BCL7
Protein Interaction Partner: RELB,RELB,SMARCA2
Protein Size: 231 -
Molecular Weight
- 25 kDa
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Gene ID
- 605
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NCBI Accession
- NM_020993, NP_066273
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UniProt
- Q4VC05
Target
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