Brain-Derived Neurotrophic Factor (BDNF) Peptide
BDNF
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN973798
Quick Overview for Brain-Derived Neurotrophic Factor (BDNF) Peptide (ABIN973798)
Target
BDNF
(Brain-Derived Neurotrophic Factor (BDNF))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-BDNF antibody (Catalog #: ARP41970_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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Background
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BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression BDNF is reduced in both Alzheimer's and Huntington disease patients. BDNF may play a role in the regulation of stress response and in the biology of mood disorders.The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene, but the full-length nature of only some could be determined.
Alias Symbols: MGC34632
Protein Interaction Partner: BDNF,CADPS2,CPE,ESR1,MBTPS1,NCAM1,NOS3,NTF3,NTF4,NTRK2,SORT1,NTRK2
Protein Size: 247 -
Molecular Weight
- 27 kDa
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Gene ID
- 627
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NCBI Accession
- NM_001709, NP_001700
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UniProt
- P23560
Target
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