Bone Morphogenetic Protein 4 (BMP4) (C-Term) Peptide
BMP4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973843
Quick Overview for Bone Morphogenetic Protein 4 (BMP4) (C-Term) Peptide (ABIN973843)
Target
BMP4
(Bone Morphogenetic Protein 4 (BMP4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- NWAQLRPLLV TFGHDGRGHA LTRRRRAKRS PKHHSQRARK KNKNCRRHSL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-BMP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Bone Morphogenetic Protein 4 (BMP4) (AA 293-408) peptide
BMP4 Reactivity: Human Host: Escherichia coli (E. coli) SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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Background
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The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Alias Symbols: BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
Protein Interaction Partner: BMP4,BMPR1B,CHRD,BGN,BMP4,BMP8B,BMPER,BMPR1A,BMPR1B,BMPR2,CHRDL1,CHRDL2,GREM2,HTRA1,NOG,SOSTDC1,STAP2,ZFYVE9,BMPR1A,BMPR1B,BMPR2,SOSTDC1,TWSG1
Protein Size: 408 -
Molecular Weight
- 46 kDa
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Gene ID
- 652
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NCBI Accession
- NM_001202, NP_001193
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UniProt
- P12644
Target
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