Bone Morphogenetic Protein 4 (BMP4) (AA 293-408) Peptide
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- Target See all BMP4 products
- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
- Peptide Type
- Recombinant
- Protein Region
- AA 293-408
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MSPKHHSQRA RKKNKNCRRH SLYVDFSDVG WNDWIVAPPG YQAFYCHGDC PFPLADHLNS TNHAIVQTLV NSVNSSIPKA CCVPTELSAI SMLYLDEYDK VVLKNYQEMV VEGCGCR
- Characteristics
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Purified recombinant Human BMP4 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - Purity
- > 95 % pure
- Endotoxin Level
- < 1.0 EU per µg of protein (determined by LAL method)
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- Application Notes
- BMP4 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied as a liquid in 10 mM sodium citrate buffer, pH 3.5, containing 10 % glycerol.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
- Synonyms
- BMP2B Peptide, BMP2B1 Peptide, MCOPS6 Peptide, OFC11 Peptide, ZYME Peptide, Bmp-4 Peptide, Bmp2b Peptide, Bmp2b-1 Peptide, Bmp2b1 Peptide, BOMPR4A Peptide, bmp-4 Peptide, zbmp-4 Peptide, zgc:100779 Peptide, BMP-4 Peptide, XBMP-4 Peptide, bmp2b Peptide, bmp2b1 Peptide, bmp4 Peptide, ofc11 Peptide, xbmp4 Peptide, zyme Peptide, BMP4 Peptide, bone morphogenetic protein 4 Peptide, bone morphogenetic protein 4 L homeolog Peptide, bone morphogenetic protein 4 S homeolog Peptide, BMP4 Peptide, Bmp4 Peptide, bmp4 Peptide, bmp4.L Peptide, bmp4.S Peptide
- Background
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Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic protein family which belongs to the TGF-beta superfamily. This protein is a vital regulatory molecule that functions throughout bone and cartilage development, specifically tooth development, limb formation, bone induction, and fracture repair. In human embryonic development, BMP- 4 is required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. And it is overexpressed in patients with fibrodysplasia ossificans progressiva. Recombinant BMP-4 was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Alternative Names: Bone morphogenetic protein 4 BMP 4 protein, BMP 4 protein, DVR4 protein, BMP 4, BMP-4 protein, BMP-4, BMP-2B protein, BMP4, ZYME., BMP2B1 protein, BMP2B protein - Molecular Weight
- 13.2 kDa (117 AA)
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