Bone Morphogenetic Protein 6 (BMP6) (N-Term) Peptide
BMP6
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all BMP6 products
- BMP6 (Bone Morphogenetic Protein 6 (BMP6))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DGGSPGRTEQ PPPSPQSSSG FLYRRLKTQE KREMQKEILS VLGLPHRPRP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BMP6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BMP6 (Bone Morphogenetic Protein 6 (BMP6))
- Synonyms
- BMP6 Peptide, zgc:113595 Peptide, vgr Peptide, vgr-1 Peptide, vgr1 Peptide, VGR Peptide, VGR1 Peptide, D13Wsu115e Peptide, Vgr1 Peptide, bone morphogenetic protein 6 Peptide, bone morphogenetic protein 6 S homeolog Peptide, BMP6 Peptide, bmp6 Peptide, bmp6.S Peptide, Bmp6 Peptide
- Background
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The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
Alias Symbols: VGR, VGR1
Protein Interaction Partner: ACVR2A,BMPER,BMPR1A,BMPR1B,BMPR2,CHRDL2,NCOA3,SMAD5,SOSTDC1,ACVR2A,ACVR2B,BMPR1A,BMPR2
Protein Size: 513 - Molecular Weight
- 57 kDa
- Gene ID
- 654
- NCBI Accession
- NM_001718, NP_001709
- UniProt
- P22004
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